Preparative HPLC for Pharmaceutical Drug Purification: Methodologies and Case Studies
Preparative HPLC for Pharmaceutical Drug Purification: Methodologies and Case Studies
Purification is a critical step in drug development and manufacturing. While techniques such as extraction and crystallization are commonly used, they may not always be effective for complex mixtures, racemates, and low levels of target compounds. In such cases, preparative HPLC offers a powerful alternative that can achieve high levels of purity. As such, mastering the art of preparative HPLC is vital to ensure the purity, quality, and safety of pharmaceutical drug substances.
In this webinar, our team of experts will provide an in-depth look at the basics of preparative HPLC, various chromatographic methodologies, method development and optimization, loading studies, and fractionation. We will also delve into feed solution preparations, analysis, solvent reduction/drying methodologies, and the major challenges associated with preparative HPLC.
Through this webinar, we intend to shed light on the capabilities of preparative HPLC and address key questions, including:
In this webinar, our team of experts will provide an in-depth look at the basics of preparative HPLC, various chromatographic methodologies, method development and optimization, loading studies, and fractionation. We will also delve into feed solution preparations, analysis, solvent reduction/drying methodologies, and the major challenges associated with preparative HPLC.
Through this webinar, we intend to shed light on the capabilities of preparative HPLC and address key questions, including:
- What are the pros and cons compared to other techniques?
- When to use preparative HPLC – and when not to?
- How much can be purified and isolated?
- What are the major challenges?
Additionally, we will supplement the presentation with real-world examples and case studies of preparative HPLC projects carried out by our team at Ardena.
By attending this webinar, you will gain understanding of the capacities of preparative HPLC, learn from our case studies, and be equipped with the knowledge and skills needed to make informed decisions on the purification and isolation of pharmaceutical drug substances. Join us to master the art of preparative HPLC.
